L-Tryptophan#73-22-3
L-tryptophan is the L-enantiomer of tryptophan. It functions as an antidepressant, nutraceutical, and micronutrient, while also serving as a metabolite in humans, mice, Saccharomyces cerevisiae, Escherichia coli, and plants.
L-Tryptophan Chemical Properties
|
Melting point |
289-290 °C (dec.)(lit.) |
|
alpha |
-31.1 º (c=1, H20) |
|
Boiling point |
342.72°C (rough estimate) |
|
density |
1.34 |
|
bulk density |
400kg/m3 |
|
refractive index |
-32 ° (C=1, H2O) |
|
storage temp. |
2-8°C |
|
solubility |
20% NH3: 0.1 g/mL at 20 °C, clear, colorless |
|
form |
powder |
|
pka |
2.46(at 25℃) |
|
color |
White to yellow-white |
|
PH |
5.5-7.0 (10g/l, H2O, 20℃) |
|
Odor |
wh. cryst. or cryst. odorless powd., sl. bitter taste |
|
biological source |
non-animal source |
|
Optical Rotation |
[α]20/D 31.5±1°, c = 1% in H2O |
|
Water Solubility |
11.4 g/L (25 ºC) |
|
Merck |
14,9797 |
|
BRN |
86197 |
|
Stability: |
Stable. Incompatible with strong acids, strong oxidizing agents. |
|
InChIKey |
QIVBCDIJIAJPQS-VIFPVBQESA-N |
|
LogP |
0.704 (est) |
|
CAS DataBase Reference |
73-22-3(CAS DataBase Reference) |
|
NIST Chemistry Reference |
L-Tryptophan(73-22-3) |
|
EPA Substance Registry System |
L-Tryptophan (73-22-3) |
|
Absorption |
cut-off at 326nm in 0.5 M HCl at 0.5M |
Product Application of L-Tryptophan#73-22-3
Amino acid-type drugs can be formulated into amino acid infusions, often combined with iron and vitamins. Co-administration with vitamin B6 may alleviate depression and aid in the prevention and treatment of skin diseases; when used as a sleep sedative, it can be combined with L-dopa for Parkinson's disease treatment. These drugs are carcinogenic in experimental animals and may cause adverse reactions such as nausea, anorexia, and asthma. Combination with monoamine oxidase inhibitors should be avoided.
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